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Top 10 Largest Multinationals and Major Companies in Brooklyn NY

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Top 10 Largest Multinationals and Major Companies in Brooklyn NY

Brooklyn: The Engine of Innovation and Creative Tech

Brooklyn has evolved from an industrial powerhouse into a global hub for tech startups, creative agencies, and advanced manufacturing. Often referred to as Manhattan’s “cool younger sibling,” it is now a massive economic force in its own right. From the tech campuses of the Brooklyn Navy Yard to the trendy corporate offices in DUMBO and Williamsburg, Brooklyn attracts the world’s most innovative brands. For aznewyork.com, Brooklyn represents the future of the New York corporate landscape.

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Today, Brooklyn is home to “Unicorns,” global e-commerce leaders, and major healthcare systems. The borough’s mix of historic industrial spaces and modern glass towers creates a unique environment where heritage industries meet the digital economy.

Brooklyn’s high-growth economy demands specialized expertise:

“Market Pulse: The ‘Brooklyn Tech Triangle’—linking Downtown Brooklyn, DUMBO, and the Navy Yard—has become a global magnet for AI, FinTech, and Green Manufacturing, offering a vibrant alternative to the traditional high-rises of Manhattan.”

Brooklyn Economic Zones: Where the Power Is
Economic District Primary Industry Key Profile
Brooklyn Navy Yard Modern Manufacturing & Tech. AI Labs, Robotics, Media Studios.
DUMBO Creative Agencies & Digital. Etsy, AdTech, High-End Design.
Industry City (Sunset Park) Design, Fashion & Logistics. Innovation Hubs & Creative HQs.

Regional Synergies: Connecting the Boroughs

Brooklyn acts as the bridge between Manhattan’s finance and the logistics hubs of the surrounding area:

Nearby Hub Strategic Role Guide Link
Manhattan (Financial Dist) Capital & Investment Source Companies in Manhattan
Queens (Long Island City) Tech Expansion & Logistics Companies in Queens
Staten Island E-commerce Fulfillment Centers Companies in Staten Island

Strategy Note: Brooklyn is the ideal location for “B-Corp” and sustainability-focused multinationals. The borough’s talent pool is young, diverse, and highly skilled in digital-first operations, making it the premier destination for companies escaping the traditional Midtown office model.

Ranking: Top 10 Largest Multinationals and Major Companies in Brooklyn NY

This list highlights the billion-dollar leaders and major employers calling Brooklyn home in 2026.

1. Etsy, Inc.

Address: 117 Adams St, Brooklyn, NY 11201 (DUMBO)

Phone: (718) 855-7955

Website: etsy.com

Sector: E-commerce & Technology

Consultant’s View: Etsy is Brooklyn’s corporate crown jewel. Their headquarters in DUMBO embodies the borough’s creative-tech spirit. As a multi-billion dollar global marketplace, they are the largest tech company natively based in Brooklyn.

2. Maimonides Health

Address: 4802 10th Ave, Brooklyn, NY 11219

Phone: (718) 283-6000

Website: maimo.org

Sector: Healthcare & Medical Research

Consultant’s View: Maimonides is Brooklyn’s largest employer and one of the premier academic medical centers in the United States. Its specialized heart and cancer centers attract top-tier medical talent and investment to the borough.

3. ElevenLabs (Unicorn HQ)

Address: Brooklyn Navy Yard, Brooklyn, NY 11205

Website: elevenlabs.io

Sector: Artificial Intelligence & Software

Consultant’s View: Representing the “New Brooklyn,” ElevenLabs is a global leader in AI voice technology. Their presence in the Navy Yard cements Brooklyn’s status as the top hub for Artificial Intelligence research in New York.

4. NYU Langone Hospital — Brooklyn

Address: 150 55th St, Brooklyn, NY 11220

Phone: (718) 630-7000

Website: nyulangone.org

Sector: Healthcare & Life Sciences

Consultant’s View: Part of the world-class NYU Langone system, this massive facility in Sunset Park is a pillar of the local economy, employing thousands and driving significant B2B healthcare demand in the region.

5. MakerBot (Stratasys)

Address: One MetroTech Center, Brooklyn, NY 11201

Phone: (347) 334-6800

Website: makerbot.com

Sector: Advanced Manufacturing (3D Printing)

Consultant’s View: MakerBot revolutionized desktop 3D printing from its Brooklyn base. Now part of Stratasys, it remains at the forefront of the borough’s “Next-Gen Manufacturing” movement centered in MetroTech.

6. Rent the Runway

Address: 10 Jay St, Brooklyn, NY 11201

Phone: (212) 524-6860

Website: renttherunway.com

Sector: E-commerce & Fashion-Tech

Consultant’s View: A pioneer in the “shared economy” for fashion, Rent the Runway operates its massive tech and corporate hub in DUMBO, managing complex global logistics and a high-valuation inventory.

7. National Grid (NY Headquarters)

Address: 1 MetroTech Center, Brooklyn, NY 11201

Phone: (718) 643-4050

Website: nationalgrid.com

Sector: Energy & Utilities

Consultant’s View: National Grid manages the energy infrastructure for millions. Their major corporate presence in Downtown Brooklyn makes them one of the most stable and significant corporate entities in the borough.

8. Vice Media Group

Address: 289 Kent Ave, Brooklyn, NY 11249

Phone: (718) 599-3101

Website: vice.com

Sector: Media & Entertainment

Consultant’s View: Headquartered in Williamsburg, Vice Media is a global news and content powerhouse. Despite industry shifts, its Brooklyn HQ remains a central node for international digital journalism and media production.

9. Ava Labs

Address: DUMBO, Brooklyn, NY 11201

Website: avalabs.org

Sector: Blockchain & FinTech

Consultant’s View: Leading the blockchain revolution, Ava Labs is the force behind the Avalanche network. Their Brooklyn headquarters is a key destination for FinTech talent migrating from Wall Street.

10. Huge Inc.

Address: 45 Main St, Brooklyn, NY 11201

Phone: (718) 625-4843

Website: hugeinc.com

Sector: Advertising & Experience Design

Consultant’s View: Huge is one of the world’s leading digital agencies. Their massive headquarters in DUMBO has helped define the borough’s reputation as the global capital for digital design and branding.


Explore More Exclusive Guides from aznewyork.com

Most Searched Tags: Companies in Brooklyn

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