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10 Best Official CVS Pharmacies in NYC

10 Best Official CVS Pharmacies in NYC

Where to find America’s leading pharmacy and health hub in New York City.

An investment in your health is paramount, and CVS has established itself as a cornerstone of community wellness in the United States.

In New York City, a place that never stops, having 24/7 access to prescriptions, health services, and everyday essentials is a necessity. Finding an official CVS Pharmacy is the key to reliable pharmaceutical care, convenient MinuteClinic services, and a vast selection of health products.

The experience of visiting a major CVS in NYC is one of unparalleled convenience. Many locations operate around the clock, serving as brightly-lit beacons for late-night needs. Beyond the pharmacy counter, these stores offer everything from groceries and beauty supplies to photo printing and immunizations. With a focus on integrated health, the staff are trained to help you manage your prescriptions, find over-the-counter solutions, and navigate your wellness journey.

This guide, a special curation by AZ New York, is your essential map to the 10 best and most strategically located official CVS Pharmacy destinations in the city.

In a city that never sleeps, a 24-hour CVS is more than a pharmacy; it’s an essential part of the neighborhood’s infrastructure for health and convenience.

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4 Tips for Visiting a CVS Pharmacy in NYC

  • Use the CVS App: The app is your best tool. You can manage prescriptions, order refills for pickup, check MinuteClinic wait times, and access your ExtraCare deals all from your phone.
  • Check for 24-Hour Locations: Not all NYC locations are open 24/7. If you need something late at night, use the store locator on the CVS website or app to find the nearest 24-hour pharmacy.
  • Sign Up for ExtraCare: The ExtraCare rewards program is essential for saving money. It’s free to join and gives you access to weekly sale prices and earns you 2% back in ExtraBucks Rewards on most purchases.
  • Book MinuteClinic Appointments Online: For services like vaccinations, physicals, or minor illness treatment, you can view wait times and book an appointment online at the official MinuteClinic page to save time.

Keep an Eye On: MinuteClinic & HealthHUB Locations.

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Many CVS stores have evolved into comprehensive health destinations. MinuteClinic locations are staffed by nurse practitioners and physician associates who can diagnose, treat, and write prescriptions for common illnesses, injuries, and skin conditions. Select stores are also designated as HealthHUBs, offering an expanded range of health services and products, including wellness rooms for consultations and durable medical equipment.

Frequently Asked questions (FAQ)

Do I need an appointment to get a flu shot at CVS?

While appointments are recommended to ensure minimal wait time, most CVS Pharmacy and MinuteClinic locations accept walk-ins for flu shots and other common immunizations, subject to availability.

Can I return an item I bought on CVS.com to a physical store in NYC?

Yes, most items purchased on CVS.com can be returned to any CVS Pharmacy store within 60 days of purchase. You will need to bring the original packing slip or the shipping confirmation email.

How does the prescription delivery service work in NYC?

CVS offers same-day and 1-2 day prescription delivery to eligible addresses in NYC for a small fee. You can select the delivery option when you refill your prescription through the app or website.

Ranking: The 10 Best Official CVS Pharmacies in NYC

Below, check out the key official CVS Pharmacy locations in the city, in a special curation by AZ New York.

1. CVS – Times Square

Operating 24/7 in the heart of the world’s busiest intersection, this massive two-story CVS is a landmark in its own right. It serves a constant stream of tourists and locals with a huge selection of health products, souvenirs, and convenience items, plus a full-service pharmacy.

Address: 2 Times Square, New York, NY 10036
Type: 24/7 Flagship Pharmacy
Borough: Manhattan
Highlight: A massive, 24/7 flagship store at the “Crossroads of the World.”

2. CVS – Herald Square

Located directly across from Macy’s, this 24/7 store is another critical hub for Midtown. Its proximity to Penn Station and Madison Square Garden makes it an essential stop for commuters, event-goers, and shoppers in one of the city’s busiest districts.

Address: 200 W 34th St, New York, NY 10001
Type: 24/7 Major Pharmacy
Borough: Manhattan
Highlight: A key 24/7 location serving the Penn Station and Herald Square area.

3. CVS – Grand Central (42nd & Lexington)

This 24-hour CVS is strategically located just steps from Grand Central Terminal, making it indispensable for the thousands of commuters who pass through the area daily. It’s a go-to for last-minute travel necessities and prescription pickups on the way home.

Address: 150 E 42nd St, New York, NY 10017
Type: 24/7 Commuter Hub
Borough: Manhattan
Highlight: The essential 24/7 pharmacy for Grand Central commuters.

4. CVS – Union Square

Serving as the main pharmacy for the vibrant Union Square neighborhood, this large, 24/7 location caters to NYU students, local residents, and commuters. It has a comprehensive selection and is a reliable anchor for the community’s health needs.

Address: 150 E 14th St, New York, NY 10003
Type: 24/7 Major Pharmacy
Borough: Manhattan
Highlight: A vital 24/7 resource for the bustling Union Square area.

5. CVS – Columbus Circle

Situated at the southwest corner of Central Park, this CVS is a key location for residents of the Upper West Side and Midtown West. It features a MinuteClinic, making it a convenient stop for both pharmacy needs and minor medical services.

Address: 241 W 57th St, New York, NY 10019
Type: Pharmacy with MinuteClinic
Borough: Manhattan
Highlight: A major location with a MinuteClinic near Central Park.

6. CVS – Upper West Side (72nd & Broadway)

Located in the heart of a major residential neighborhood, this CVS is a lifeline for local families and residents. It provides essential pharmacy services, groceries, and household items to a dense and active community.

Address: 2089 Broadway, New York, NY 10023
Type: Neighborhood Pharmacy
Borough: Manhattan
Highlight: An essential pharmacy for the Upper West Side residential community.

7. CVS – Upper East Side (86th & Lexington)

Serving another of Manhattan’s premier residential areas, this location is a critical health hub for the Upper East Side. Its proximity to a major subway stop makes it a convenient and consistently busy store for the neighborhood.

Address: 1294 Lexington Ave, New York, NY 10028
Type: Neighborhood Pharmacy
Borough: Manhattan
Highlight: A cornerstone pharmacy for the residents of the Upper East Side.

8. CVS – Wall Street

Catering to the Financial District’s high-powered workforce, this CVS is perfectly located for busy professionals. It’s a key spot for picking up prescriptions and essentials during the workday in the heart of downtown Manhattan.

Address: 45 Wall St, New York, NY 10005
Type: Financial District Hub
Borough: Manhattan
Highlight: The go-to pharmacy for the Wall Street and Financial District area.

9. CVS – Downtown Brooklyn (City Point)

Located within the bustling City Point shopping center, this is a flagship location for Brooklyn. It’s a modern, spacious store that serves as a vital health and retail anchor for the rapidly growing Downtown Brooklyn community.

Address: 1 Dekalb Ave, Brooklyn, NY 11201
Type: Major Brooklyn Pharmacy
Borough: Brooklyn
Highlight: A large, modern pharmacy in the heart of Downtown Brooklyn’s retail hub.

10. CVS – Long Island City

Serving one of the fastest-growing neighborhoods in NYC, this CVS is essential for the residents and workers of Long Island City. It provides crucial pharmacy and retail services to a community that has seen explosive development.

Address: 2130 44th Dr, Long Island City, NY 11101
Type: Neighborhood Pharmacy
Borough: Queens
Highlight: The key pharmacy for the booming Long Island City neighborhood.

All research and the final selection of the locations in this guide were carried out by the team at AZ New York. These are the primary official CVS Pharmacy destinations in the city.


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